Angioid streaks in thalassaemia major.

Angioid streaks in a case of beta thalassaemia major.

Angioid streaks in beta thalassaemia minor.

We report what we believe to be the first recorded case of angioid streaks in a patient with beta thalassaemia minor. The occurrence of angioid streaks in a patient with a relatively normal iron balance and only very mild haemolysis may be explained by the combination of pregnancy with associated multiple transfusions in a myopic patient where an inherent defect in Bruch's membrane may exist.

Angioid Streaks in Psuedoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a hereditary disorder that affects primarily the elastic tissues of skin, eyes and blood vessels. Its estimated prevalence is thought to be 1:25,000 100,000. PXE patients also carry an increased risk for cardiovascular and gastrointestinal diseases. Early diagnosis can play a crucial role in preventing early loss of vision and systemic complications in these pa...

Angioid streaks and elastorrhexis.

ANGIOID streaks are thought to be due to breaks in the elastic lamina of Bruch's membrane. Ophthalmoscopically they present a jagged peripapillary ring which may be incomplete and from which radiate irregular spokes of width similar to retinal vessels. With time, they may progress, or become less distinct. Their colour varies from reddish-brown to dark brown according to the density of the over...

Classification of angioid streaks.

ANGIOID streaks of the retina were first described by Doyne (1889). They have since been the subject of much controversy. More than 200 cases have been reported in the literature, but histological studies have been few and the changes described have varied. The condition is frequently associated with pseudoxanthoma elasticum, with cardiovascular disease, and with Paget's disease of bone. A simi...